Phytochemical Screening and In Vitro Antioxidant and Anti-inflammatory Activities of Aerial Parts of Euphorbia hirta L.

Euphorbia hirta L (Euphorbiaceae) also called asthma herb has long been prescribed in traditional medicine because it exhibits diverse pharmacological actions due to the presence of alkaloids, flavonoids, polyphenols, triterpenoids, and saponins. The present study is aimed at phytochemical antioxidant activity anti-inflammatory screening E. hirta. Extraction dried powder was performed followed by using color reactions. Total phenolic content (TPC) total flavonoid (TFC) extracts were estimated Folin-Ciocalteu Aluminum chloride method respectively. studied 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method. Anti-inflammatory protein denaturation vitro bioassay. Phytochemical showed compounds. TPC, TFC (IC50) extract found as 288.10 mg gallic acid equivalent per gram (GAE/g), 29.36 quercetin (QE/g) 32.23 µg/mL (p<0.05) Diclofenac sodium maximum inhibition 91.28% 68.20% respectively concentration 1000 compared with control (p>0.05). compounds flavonoids exert activities their ability. demonstrated may be rationale behind some its folkloric uses responsible for effects. Thus, can considered a good source antioxidants actions, which might beneficial combating oxidative stress.